NCLEX · Aging and Older Adults

Which of the following is a NORMAL physiological change associated with aging?

Correct answer

Decreased renal clearance — kidney function declines progressively with age, affecting drug elimination and making older adults more susceptible to medication toxicity

  1. A Decreased blood pressure in all older adults
  2. B Decreased renal clearance — kidney function declines progressively with age, affecting drug elimination and making older adults more susceptible to medication toxicity
  3. C Improved balance and faster reaction time
  4. D Increased muscle mass

Why this is the answer

Normal physiological changes with aging:

Renal: GFR decreases approximately 1% per year after age 40; reduced creatinine clearance means medications eliminated renally accumulate to higher levels at the same dose — dosage adjustments are often required.

Musculoskeletal: Muscle mass decreases (sarcopenia); bone density decreases; height decreases.

Cardiovascular: Maximum heart rate decreases; cardiac reserve decreases; blood pressure often increases (not decreases) with age due to arterial stiffness.

Respiratory: Vital capacity decreases; chest wall compliance decreases.

Sensory: Visual acuity decreases; hearing loss (presbycusis); taste and smell decline; GI: Decreased GI motility (constipation risk); decreased gastric acid.

Neurological: Slowed reaction time; decreased balance; memory retrieval (not storage) slows. Normal aging changes ≠ disease — these are expected, not pathological.

Source: NCLEX-PN, Normal Aging Changes

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About this topic: Aging and Older Adults

Aging and older-adult questions cover normal changes of aging versus disease, fall and injury prevention, polypharmacy, and promoting independence and safety in older clients. This is one of 8 PN: Health Promotion and Maintenance questions on aging and older adults, each with a full explanation on a single study page.

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