NCLEX · Immunizations and Health Screening

A nurse is teaching a 45-year-old woman about cervical cancer screening. Which schedule is currently recommended?

Correct answer

Pap smear every 3 years (ages 21-65) OR Pap smear with HPV co-testing (co-test) every 5 years (ages 30-65); no Pap needed before age 21 regardless of sexual history

  1. A Pap smear every 3 years (ages 21-65) OR Pap smear with HPV co-testing (co-test) every 5 years (ages 30-65); no Pap needed before age 21 regardless of sexual history
  2. B Annual Pap smear starting at age 21
  3. C Pap smear only when symptoms occur
  4. D Monthly self-examination

Why this is the answer

CERVICAL CANCER SCREENING GUIDELINES (USPSTF/ASCCP): Ages 21-29: Pap smear (cytology) alone every 3 years; HPV testing not recommended in this age group (HPV is common and usually clears spontaneously in younger women); Ages 30-65:

Option 1: Pap smear every 3 years.

Option 2: Pap + HPV co-test every 5 years (preferred — most sensitive).

Option 3: HPV test alone every 5 years (FDA-approved primary screening); Under 21: Do NOT screen regardless of sexual history initiation (normal HPV clearance; colposcopy for abnormal results is harmful in this age group); Over 65: Can discontinue if 3 consecutive negative cytologies or 2 consecutive negative co-tests in past 10 years with last test within 5 years AND no history of CIN2+ or cervical cancer.

Nursing role: Correct common misconception that annual Pap smears are needed; explain that longer intervals reflect evidence-based guidelines, not reduced care quality.

Source: NCLEX-RN HP — Cancer Screening, Cervical Cancer Pap Schedule

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About this topic: Immunizations and Health Screening

Immunizations and screening questions cover the recommended vaccine schedules, contraindications and live-vaccine precautions, and age- and risk-based screening recommendations. This is one of 15 RN: Health Promotion and Maintenance questions on immunizations and health screening, each with a full explanation on a single study page.

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