NCLEX · Pharmacological Therapies

A client prescribed furosemide (Lasix) 40 mg IV is a nursing priority to assess which parameter BEFORE administration?

Correct answer

Serum potassium and recent urine output — furosemide is a loop diuretic that causes significant potassium wasting; administering to a hypokalaemic client can cause dangerous cardiac dysrhythmias; also assess: BP (diuretic in hypotensive client causes further drop), renal function (contraindicated in anuria)

  1. A Liver enzymes
  2. B INR level
  3. C Blood glucose
  4. D Serum potassium and recent urine output — furosemide is a loop diuretic that causes significant potassium wasting; administering to a hypokalaemic client can cause dangerous cardiac dysrhythmias; also assess: BP (diuretic in hypotensive client causes further drop), renal function (contraindicated in anuria)

Why this is the answer

Pre-furosemide assessment:

Potassium: Most critical — loop diuretics (furosemide, torsemide, bumetanide) block Na-K-Cl co-transporter in the loop of Henle; significant potassium loss with every dose; hold and notify if K+ < 3.0-3.5 mEq/L (facility-specific threshold).

Blood pressure: Hold if hypotensive per orders — diuresis on an already volume-depleted patient worsens hypotension, tachycardia, and possibly syncope.

Urine output: Anuria (no urine) contraindicates furosemide — there is nothing to diurese.

Renal function: BUN/creatinine — severe renal impairment changes dosing.

Allergies: Cross-reactivity with sulphonamide allergy (controversial — check facility policy).

Hearing: Furosemide is ototoxic, especially with high IV doses or co-administration of aminoglycosides — inquire about hearing symptoms.

Weight: Daily weights are the best measure of fluid loss/gain in patients on diuretics; establish baseline before first dose.

Source: NCLEX-PN Physiological — Pharmacology, Pre-Furosemide Assessment

Practice more questions

This question is from our NCLEX Practice Tests practice test. Take the full practice test to test your knowledge across all Pharmacological Therapies and other topics.

Take the PN: Physiological Integrity practice test →

About this topic: Pharmacological Therapies

Pharmacological therapies questions cover medication administration, dosage calculation, the rights of medication administration, common drug classes and their side effects, and when to hold a medication and report. This is one of 18 PN: Physiological Integrity questions on pharmacological therapies, each with a full explanation on a single study page.

New to this exam? Our NCLEX exam guide explains the format, scoring, and how to prepare.

Related questions

State-specific guides

Need information for your state? Our state guides cover local requirements, fees, and what to expect on exam day.