NCLEX · Safety and Infection Control

A nurse is caring for a client with Clostridioides difficile (C. diff). Which infection control measure is essential?

Correct answer

Use contact precautions and wash hands with soap and water (alcohol-based sanitizer does not kill C. diff spores)

  1. A Use airborne precautions
  2. B No special precautions needed
  3. C Use contact precautions and wash hands with soap and water (alcohol-based sanitizer does not kill C. diff spores)
  4. D Use alcohol-based hand sanitizer only

Why this is the answer

For C. DIFFICILE (C. diff — causes severe diarrhea, spread by spores): use CONTACT PRECAUTIONS (gown and gloves) AND wash hands with SOAP AND WATER — because alcohol-based hand sanitizer does NOT kill C. diff SPORES (the mechanical action of soap and water physically removes them). NCLEX safe care/infection control. Also: dedicated/disposable equipment; clean the environment with a sporicidal agent (bleach-based); private room.

Key point: C. diff (and other spore-formers) is the exception to the 'alcohol sanitizer is fine' rule — you MUST use soap and water. Norovirus is similar (soap and water preferred). Knowing that C. diff requires soap-and-water handwashing (not alcohol gel) plus contact precautions is a heavily tested NCLEX concept.

Source: NCLEX Safe Care — C. diff Precautions

Practice more questions

This question is from our NCLEX Practice Tests practice test. Take the full practice test to test your knowledge across all Safety and Infection Control and other topics.

Take the RN: Safe and Effective Care Environment practice test →

About this topic: Safety and Infection Control

Safety and infection control questions cover Standard and transmission-based precautions, isolation set-up, sterile technique, error prevention, restraints, and emergency and disaster response. This is one of 24 RN: Safe and Effective Care Environment questions on safety and infection control, each with a full explanation on a single study page.

New to this exam? Our NCLEX exam guide explains the format, scoring, and how to prepare.

Related questions

State-specific guides

Need information for your state? Our state guides cover local requirements, fees, and what to expect on exam day.