NCLEX · Safety and Infection Control

A nurse is reconciling a client's medications and finds the client is taking warfarin and was just prescribed aspirin by a different provider. What is the priority action?

Correct answer

Recognize the potential interaction (both increase bleeding risk) and notify the provider before administering — medication reconciliation is a key safety step to catch dangerous interactions and duplications

  1. A Hold both medications indefinitely
  2. B Tell the client to choose which one to take
  3. C Recognize the potential interaction (both increase bleeding risk) and notify the provider before administering — medication reconciliation is a key safety step to catch dangerous interactions and duplications
  4. D Administer both medications as prescribed

Why this is the answer

MEDICATION RECONCILIATION — CATCHING INTERACTIONS: Warfarin (anticoagulant) + aspirin (antiplatelet) = significantly increased bleeding risk; this combination requires provider awareness and may be intentional (some cardiac conditions) or an oversight from separate prescribers.

Priority: Recognize the interaction; notify the provider to confirm intent before administering; do not simply give both without clarification.

Medication reconciliation: Comparing the client's current medications across transitions of care (admission, transfer, discharge) to identify and resolve discrepancies — duplications, omissions, interactions, dosing errors; a National Patient Safety Goal; HIGH-RISK INTERACTIONS to know: anticoagulant + antiplatelet (bleeding); ACE inhibitor + potassium (hyperkalemia); multiple QT-prolonging drugs (dysrhythmia); MAOIs + many drugs/foods.

Involve: pharmacist for complex reconciliation.

Safety culture: Catching these is exactly why reconciliation exists; LPN role: participate in reconciliation, recognize potential interactions, notify the provider, advocate for client safety.

Source: NCLEX-PN Safe Care — Medication Reconciliation and Interactions

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About this topic: Safety and Infection Control

Safety and infection control questions cover Standard and transmission-based precautions, hand hygiene, fall and injury prevention, restraints, fire safety and handling hazardous materials. This is one of 35 PN: Coordinated Care questions on safety and infection control, each with a full explanation on a single study page.

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